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The HOD guides.

Get to know the treatments that can help you look and feel hotter. HOD guides put results, prices and the details of taking each treatment in plain language.

Featured guides.

Take a closer look at the treatments on your list, from the results people get to the price and routine behind them.

01Foundations

Build a treatment plan with the facts that count. Learn how to read results, compare prices and ask useful questions about your options.

Woman sitting by a bright window gently touching her cheek while applying skincare serumDo Peptide Injections Hurt?Peptide shots usually feel like a quick pinch. See what affects sting, simple ways to ease it and when to call your provider.Two women enjoying a casual conversation by a tranquil lakeside in warm daylight.What Should a First Peptide Therapy Consult Include?Learn what a thorough first peptide consult includes, from intake and labs to sourcing, safety checks and cost.Charming portrait of a woman in red jacket sitting indoors, exuding confidence and poise.How to Tell a Licensed Peptide Telehealth Clinic From a Research Chemical SellerHow to spot a licensed peptide telehealth clinic versus a research seller with visit, prescription, pharmacy checks and red flags.A blank white card resting beside an amber glass bottle and dried florals in warm sunlight.What a Peptide Certificate of Analysis ShowsA peptide COA proves only the tests listed for that batch, usually identity and purity, not sterility, approval, or pharmacy quality.Adult woman sitting by window working remotely on a laptop indoors.Which Peptide Telehealth Providers Are Best for Women, and What Does Each One Cost?Compare peptide telehealth for women with Joi+Blokes, Defy, Ageless Rx, Eden and HerKare prices, fees and monthly rate gaps.Woman sitting at a table by a sunlit window reviewing printed paperwork next to an open laptop.What to Verify About a Peptide Provider, Pharmacy and Product Before You BuyCheck a peptide pharmacy license, COA and red flags that separate licensed pharmacy care from research-chemical sales.A woman enjoys a peaceful morning stretch in bed with sunlight streaming through the window.NAD Injection Frequency: Advertised Schedules Compared With Tested RegimensHow often is NAD injected? See advertised SubQ and IV frequencies and what trials have and have not tested for energy and longevity.A woman relaxing on a bed, using a digital tablet while wearing a cozy knitted sweater.How do Superpower, Hims, and peptide clinics compare for access and cost?Superpower is $349/year for labs and a plan. Hims is $39 then $149/month plus medication. Compare access and extra costs.A woman wearing a plaid blazer gestures with her hands while speaking in aWhat Should Women Ask Before Paying a Peptide Clinic?Before paying a peptide clinic, ask if the peptide is FDA-approved or compounded, which pharmacy makes it, and what risks and follow-up are included.

02Weight

Find a weight-loss treatment that fits your goals and routine. Compare how much weight people lose, what treatment involves and what you'll pay over time.

HODBest Weight-Loss Medications for PCOS: 5 Options Ranked by EvidenceTirzepatide, semaglutide, liraglutide, metformin and orlistat ranked for women with PCOS, with trial results, side effects and pregnancy timing.HODCompounded Semaglutide vs Wegovy: What Is Actually DifferentCompounded semaglutide vs brand Wegovy: FDA approval, legal status since the shortage ended, salt forms, dosing risks and current self-pay prices.HODBest Supplements to Take on a GLP-1: 6 Picks Ranked by EvidenceProtein, fiber, vitamin D, B12, a multivitamin and creatine ranked for GLP-1 users, based on a 2025 nutrition advisory and clinical trials.HODBest Weight-Loss Medications for Women in Menopause: 6 Options RankedTirzepatide, semaglutide, the Wegovy pill and older options ranked by trial results in midlife women, with side effects and who each suits.Close-up of woman in bikini on a sandy beach with turquoise waters.Why Resting Heart Rate Rises on Semaglutide or Tirzepatide and Whether It Is DangerousWhy semaglutide and tirzepatide raise resting pulse a few beats, what happens to blood pressure and what it means for heart failure.A person practicing mindfulness and balance through yoga with a focus on the core.How to Do Your First Subcutaneous Peptide Injection Without Stinging or BruisingFirst peptide shot tips. Warm the vial, use a short needle into belly fat, and push slow to limit sting and bruising.A woman stands at a window in Dublin during sunset, basking in warm sunlight.Do You Need B12 While on Semaglutide?Do you need B12 on semaglutide? Most women do not need it routinely. Vitamin D runs low more often.Young woman sitting pensively on a cozy couch indoors, surrounded by plants. Thoughtful and contemplative mood.Planning Pregnancy on a GLP-1: What to Know About Fertility and StoppingOn a GLP-1 and planning pregnancy? How fertility returns, which birth control holds up, and when to stop before trying.A woman enjoys a quiet moment with coffee, sitting on a rattan chair bathed in natural light.Can Semaglutide Affect Your Mood?Semaglutide and mood: what trials and safety reports show on low mood, anxiety, sleep, and when to contact your prescriber.Warm close-up of a person holding a tea mug with a slice of lemon. Perfect for cozy autumn vibes.What happens when your GLP-1 dose goes up?Higher GLP-1 dose often means stronger fullness plus a 1-2 week flare of nausea. Why slow increases work and top dose isn't required.A thoughtful woman relaxing on a couch indoors with soft lighting.Why Does Semaglutide Make Some Women So Tired?Why semaglutide drains energy, how common fatigue is, what helps, and when lasting exhaustion needs labs.Woman with red hair smiling while holding a tall cocktail at a marble restaurant tableCan I Drink Alcohol While Taking Semaglutide or Tirzepatide?Can you drink alcohol on semaglutide or tirzepatide? Risks, why cravings drop, and what women report.HODWhat Does a GLP-1 Maintenance Dose Look Like After You Reach Goal Weight?After goal weight, GLP-1 maintenance is the lowest dose that holds weight steady, with dose or timing set by your prescriber.African American woman with curly hair enjoying a hot drink indoors, eyes closed, in warm sunlight.Missed Semaglutide Dose? Why Product-Specific Labels MatterIf you missed the once-daily Ozempic pill, skip it and take one tablet next morning. See why semaglutide products need separate instructions.Woman with curly dark hair looking thoughtfully out a sunlit window with warm afternoon light.Semaglutide Weight Loss Plateau: Short Stall vs Sustained PlateauShort stall or true plateau on semaglutide? How to read the trend and which details change your next step.African American woman using laptop and credit card for online shopping at home.How much does semaglutide or tirzepatide cost per month without insurance?Self-pay Wegovy costs $149 to $399 a month by dose and form. Self-pay Zepbound vials cost about $299 to $499 a month.HODWeight regain after stopping semaglutide: continuation versus stopping evidenceStopping semaglutide brings regain within a year; staying on keeps loss. See continuation vs stopping trials and maintenance.Close-up of essential oil bottle droppers on a wooden shelf in a store setting.What Is the True Monthly Cost of a Multi-Peptide Stack vs Single Peptides?Single peptides cost $150–$350/month all in; 2-peptide combos $250–$500 and 3+ peptides $400–$800 with labs and supplies.Pretty casual serious lady with hairstyle intently looking at camera while standing near stained glass window in bright luxury room of old mansionWhy won't insurance cover GLP-1s for weight loss?Medicare, work and Marketplace plans often cover GLP-1s for diabetes but exclude weight loss. See costs and the $50 Bridge option.African American woman working remotely with a laptop and smartphone in a modern office setting.Where Can Women Actually Get Retatrutide in 2026?No prescription retatrutide in 2026. Learn the only authorized routes, trial status, and risks of online vials.Close-up of a woman's hands resting on her waist, showcasing nude clothing.First GLP-1 Injection: What to Expect and How to PrepareWhat the first GLP-1 shot feels like, how to prepare, and what to ask your prescriber before day one.A stylish mature woman smiling in warm directional sunlight wearing a hoodie and leather jacket.GLP-1s for Perimenopause Weight Loss: Menopause-Specific Research and TimelinesDo GLP-1s help with perimenopause weight loss? What menopause studies show and realistic timelines from general trials.Woman kneeling outdoors in golden hour light looking at her reflection in a small hand mirror.Switching from semaglutide to tirzepatide?Switching from semaglutide to tirzepatide? See how weight results compare, how dosing restarts, and what to track after the switch.Woman with auburn hair smiling in warm sunlight while gently running her hand through her hairOral vs topical minoxidil for women: adherence, unwanted hair and tolerabilityOral vs topical minoxidil for women compared: similar scalp regrowth, more unwanted hair with oral, more scalp itch with topical.A woman in glasses applies lipstick while looking in the mirror. Bright, modern, and stylish.Semaglutide vs Tirzepatide for Weight Loss, Side Effects and Choosing TreatmentCompare semaglutide and tirzepatide for weight loss, gut side effects and staying on treatment, plus how to choose through HOD.Woman in grey athletic wear leaning on a wooden pier railing overlooking the water in golden sunlight.How Does Retatrutide Compare With Tirzepatide?Retatrutide averaged more weight loss in trials than tirzepatide, but only tirzepatide is FDA approved and available by prescription now.A woman with long hair and a pensive expression smiles softly in an outdoor setting at sunset.What results are women seeing with retatrutide?Women lost more weight than men on retatrutide in trials, with common stomach side effects. It remains investigational.Profile view of an elegant mature woman wearing a white robe and gold earrings indoorsWhat Treatments Actually Help Ozempic Face?Research on filler, Sculptra and tightening devices for hollow cheeks and loose skin after GLP-1 weight loss.Hands gently separating strands of wet auburn hair against a muted neutral backgroundDoes minoxidil help hair loss after GLP-1 weight loss?Dermatologists often use minoxidil for shedding after GLP-1 weight loss. Learn why shedding happens and what studies in women found.Woman wearing a straw sun hat and straplessHow to Fix Loose Skin After Losing Weight on Ozempic?Mild looseness after Ozempic often improves with time and firming care, while large folds usually need an in-office procedure.Woman in an orange athletic top showing defined back and shoulder muscles outdoorsHow to Avoid Losing Muscle on Semaglutide or Tirzepatide?Most GLP-1 weight loss was fat in trials. See lean splits plus training and protein habits that preserved tissue.

03Skin and Hair

Compare treatments for clearer skin and fuller hair. Get the details on results, prices and the routines that keep those results going.

HODBest Treatments for Menopause Skin Aging: 5 Options RankedSunscreen, tretinoin, in-office collagen treatments, GHK-Cu and moisturizer ranked for menopausal skin, plus what hormone therapy can and cannot do.HODBest Peptides for Skin: 4 Options Ranked by Clinical EvidenceCollagen peptides, GHK-Cu, Matrixyl and argireline ranked by human trials for wrinkles, firmness and hydration, plus why BPC-157 is not a skin peptide.HODBest Retinoids for Wrinkles: 5 Options Ranked by EvidenceTretinoin, tazarotene, adapalene, retinaldehyde and retinol ranked by wrinkle trials, irritation and access, so you can pick the right one.HODBest Treatments for Menopause Hair Thinning: 5 Options RankedMinoxidil, oral minoxidil, spironolactone, laser caps and PRP ranked by trials in women, plus what to skip for menopause hair loss.Sunlit close-up of a woman with closed eyes and glowing skin against a soft coastal backgroundDoes GHK-Cu Help with Acne Scars?GHK-Cu may help indented acne scars look smoother with microneedling. See clinic findings, limits for deep scars and breakouts.A woman applies face cream in a well-lit bathroom, emphasizing skincare routine.Can You Do Microneedling While Using Copper Peptides?Yes, GHK-Cu is often applied during or after microneedling. Learn how timing and in-office care differ from home use.An introspective woman with short hair gazes sideways, enveloped in warm outdoor light.Do Oral Collagen Peptides Do Anything for Skin and Joints?Oral collagen peptides improve skin hydration, elasticity and wrinkle depth, but did not beat placebo for knee pain or function.A beautiful woman smiles warmly while outdoors in soft sunlight.Can You Get Laser Treatments or IPL While Using Tretinoin?Yes, with a pause. Learn when to stop tretinoin before IPL or laser hair removal, when to restart, and why resurfacing differs.Woman framed by neutral curtains in warm golden window light with glowing skinCopper Peptides Skincare Routine: Fitting GHK-Cu With Vitamin C and TretinoinAlready use tretinoin and vitamin C? See where copper peptides fit, how to time GHK-Cu, and when to skip it.Intimate close-up of a woman wearing a vibrant scarf, highlighting natural beauty.Can women use minoxidil on eyebrows? What brow trials foundSmall brow trials found fuller eyebrows with minoxidil, but brow use is off-label and can irritate skin and eyes.HODNAD+ Injection Side Effects: IV Drips vs Shots Under the Skin or in MuscleNAD+ IVs tend to bring nausea and chest pressure during the drip; shots tend to bring sore spots plus milder effects.Smiling woman wearing eye patches and a white hair towel in warmGLOW vs KLOW Peptide Stack: Ingredients and Combination EvidenceGLOW vs KLOW: how ingredients differ, why KPV was added, and what single-ingredient research shows.Brunette woman touching her sleek hair in warm sunlight outdoorsMinoxidil Shedding in Women: Why Shed Hairs Cannot Show Response AloneEarly shedding on minoxidil is common, but shed count alone cannot show response. Women's trials judged hair counts and coverage at 24 to 48 weeks.Stylish woman in houndstooth coat holding file folder. Light and shadow create dramatic effect.What Kind of Doctor Prescribes Peptide Therapy?Learn which doctors prescribe peptides, what mainstream vs longevity clinics offer, and how to check a prescriber.Woman with short blonde hair applying skincare cream to her shoulder in warm natural light.Estrogen Gel vs Patch: Application, Skin Tolerance, and RoutineCompare estrogen gel vs patch for application, skin tolerance and daily routine using product labeling, without dose conversion.Woman with curly dark hair resting her hand on her cheek in directional window light.Tretinoin Purge vs Irritation: How to Tell the DifferenceHow to tell a tretinoin purge from irritation, which symptoms need prompt care, and how to start more comfortably.A woman in a blue dress sits by a window, gazing outside, capturing a moment of relaxation.What Lab Tests Should You Get Before Starting Peptides?Baseline labs before peptides include IGF-1, blood sugar, liver, kidney, cholesterol, thyroid and inflammation, plus when to recheck.Woman applying skincare in a sunlit bedroom, embracing morning relaxation and self-care.Tretinoin vs Retinol for Wrinkles: Evidence, Tolerability, and RoutineTretinoin vs retinol for wrinkles: how results, dark spots, irritation and nightly routine compare.Profile portrait of a woman with glowing skin illuminated by warm golden hour sunlight.What Is the Glow Peptide Stack?Glow blend combines GHK-Cu, BPC-157 and TB-500 for skin and soft tissue. See what is inside and what human research shows.Woman in a white shirt holding a glass dropper and skincare bottles in warm ambient lightHow Much Does GHK-Cu Cost Per Month?GHK-Cu runs $30-$120 a month for serums and $80-$200+ for prescription creams, plus labs and supplies.Close-up profile of a woman's face illuminated by warm, directional light highlighting her glowing skin.Topical vs Injectable GHK-Cu for Skin: What Does the Evidence Show?Compare topical vs injectable GHK-Cu for skin goals, study routes and practical differences.Woman applying face cream in bathroom, focusing on skincare routine with natural reflection in mirror.Why Skin Can Look Worse After Starting Copper PeptidesWorse skin after copper peptides is most often irritation. See how that differs from unproven purge claims and what to do next.Detailed view of an amber glass bottle with a funnel, perfect for laboratory setups.How Do I Reconstitute and Store Peptides Properly?How to mix peptides with bacteriostatic water, refrigerate mixed vials, and use the 28-day rule for safe storage.Brunette woman with curly hair closes her eyes and gently touches her cheek in warm light.How Long Does GHK-Cu Take to Work on Skin?GHK-Cu for skin: hydration in 2 to 4 weeks, softer lines by week 4, and firmer-looking skin through weeks 8 to 12 with steady use.

Your HOD plan

Choose your next move.

Tell us what you want for your weight, skin, hair or sex life. Start with the HOD quiz to see your plan.

04Body

Get specific about treatments for body shape and firmness. See what changes they can make, how long results take and what they cost.

HODBest Peptides for Injury Recovery: 4 Options Ranked by Human EvidenceCollagen peptides, TB-500, BPC-157 and GHK-Cu ranked by human evidence for tendon, ligament and joint recovery, with FDA status and risks.A peaceful moment captured as a woman closes her eyes, enjoying the sun on a city balcony.Does BPC-157 Help with Chronic Lower Back Pain or Disc Herniation?No human studies test BPC-157 for back pain or herniated discs; evidence is limited to rat cord and tendon models.A woman enjoys a relaxing cup of tea, creating a cozy and tranquil atmosphere.BPC-157 for Gut Problems: What Has Been Tested in Humans?BPC-157 gut testing in people stops at early safety work and an unpublished colitis trial, with bowel healing seen only in rats.HODHow Long Does BPC-157 Take to Work on an Injury?Pain may ease in days to weeks on BPC-157, but tendon repair takes months. What human data show.Woman with wavy hair outdoors in golden sunlight touching her lip thoughtfully.What Is KPV Peptide Used For?KPV is studied for gut and skin inflammation in lab and animal models, with limited human data on redness or repair.A woman balances barefoot on a stone wall by the sea during a serene evening in Weligama, Sri Lanka.BPC-157 for Tendon Injury EvidenceBPC-157 for tendon injury: rat Achilles results, newer repair findings, and what human data show.Full body of young flexible female athlete in sportswear doing Revolved Head to Knee stretching asana during yoga session in light studioOral vs Injectable BPC-157: Which Route Fits Your Goal?Oral vs injectable BPC-157 by goal: gut lining contact versus tendon and joint injection signals from animal work and one small knee report.A detailed view of a physiotherapy session with hand placement on shoulder indoors.What Is the Wolverine Peptide Stack, and Who Is It For?Wolverine stack pairs BPC-157 with TB-500 for muscle, tendon and ligament strain. Learn what's in it, who asks about it and who should skip it.Close-up of hands with manicured nails holding a dropper over a green serum bottle.How Do Peptide Units, Milligrams, and Syringe Markings Relate?U-100 units measure liquid volume, not drug amount. See how units convert to mL and milligrams using vial strength.Woman sitting on a living room rug packing clothes into an open white carry-on suitcaseHow should prescription peptides be stored while traveling?Bring peptides in carry-on with frozen packs. Powder travels best; mixed vials need steady cold and fast refrigeration.Woman wearing a woven straw hat with warm sunlight filtering across her freckled face.What Is TB-500 Used For, and What Evidence Supports It?TB-500 is sold for repair and recovery, but human trials tested parent thymosin beta-4 for eye, skin and heart uses.

05Libido

Explore treatments for a more satisfying sex life. Learn how they work, what results to expect and what you'll pay.

HODBest Treatments for Hot Flashes: 6 Options Ranked by EvidenceEstrogen, Veozah, Lynkuet, low-dose paroxetine, gabapentin and CBT ranked by trial results, with safety rules and who each suits.A senior woman elegantly poses in a colorful dress on a rooftop during a warm sunset in the city.Can You Take PT-141 While on HRT?PT-141 has no listed interaction with HRT, but Vyleesi is approved only for premenopausal women, so menopausal use is off-label.A woman sleeping peacefully in bed under a warm knit blanket in morning sunlight.Can Birth Control Pills Cause Low Libido?Can birth control pills lower libido? Most notice no change, some notice less desire. Learn why it happens and what to track.Woman wearing an off-shoulder top and delicate necklaces surrounded by blooming pink flowers in warm sunlightDoes DHEA help low libido in perimenopause?Oral DHEA did not beat placebo for low libido, raised hormones in blood, and was not studied in perimenopause.Adult woman savoring water by a window, creating a serene indoor ambiance.How much does menopause hormone therapy cost per month without insurance?Without insurance, menopause HRT runs $10 to over $500 a month. Compare pills, patches, rings and coupon prices.A young woman with curly hair sleeping peacefully in a cozy bed with knitted blankets.Sermorelin sleep results: anecdotes, growth hormone, and measured sleepNighttime GHRH bursts added deep and dream sleep in young volunteers, but a higher GH level alone did not mean better sleep.Bare midriff of a person resting comfortably beneath crisp white sheets and pillows in soft warm lightKisspeptin vs PT-141 in Women: Study Populations and Measured OutcomesPT-141 vs kisspeptin for low desire in women: who was studied and what each trial actually measured.Woman in a black top and jeans relaxing on a bed beside a bright windowLow Libido on HRT? Why Desire Can Stay FlatHRT helped flashes and sleep but desire stayed flat? Why estrogen alone misses libido and what added testosterone shows.A contemplative woman in a denim jacket reading a book at an outdoor table, India.How Do Semax and Selank Differ?Semax was studied for thinking and stroke recovery, Selank for anxiety and fatigue. See how origins, signals and history differ.Woman reclining on a sunlit daybed surrounded by textured pillows and leafy indoor plantsIs Testosterone Worth It for Women's Low Libido?Testosterone may add a small libido gain after menopause, with hair growth and acne common and long-term breast effects uncertain.A woman in lingerie gazes through a window in a stylish living room setting.What does kisspeptin cost and where can women actually get it?No routine kisspeptin prescription or set price for desire. Trials are the legitimate route; early brain-response work was hospital-only.A relaxed woman in a floral shirt enjoys a hot drink while sitting in a bright, cozy room.Starting HRT in perimenopause: which symptoms and history matter?Starting HRT in perimenopause? Which symptoms point to hormones, what history changes the plan, and why desire alone doesn't decide it.Woman with curly hair enjoys a calm morning in a cozy bedroom, smiling in the sunlight.Vaginal Estrogen vs Systemic HRT: Local and Whole-Body Treatment GoalsVaginal estrogen eases dryness and urgency locally; systemic HRT eases hot flashes. Neither restores desire alone.A woman posing with artistic shadows from blinds creating a serene and playful mood.What Side Effects Can Women Experience With PT-141?PT-141 side effects in women include nausea, flushing, headache and brief blood pressure rise. See rates, duration and who should avoid it.Artistic capture of female legs elegantly posed on sunlit white fabric, emphasizing grace and beauty.How Quickly Does PT-141 Work, and How Long Do Effects Last?Take PT-141 at least 45 minutes before sex. Blood levels peak around 1 hour; FDA says how long benefit lasts is unknown.Close-up of a couple embracing on a bed, showcasing love and intimacy.Why Did My Sex Drive Drop in Perimenopause?Late perimenopause often brings lower desire, more pain with sex and less comfort. Learn timing and options for distressing low desire.Amber glass dropper bottle resting in a wooden bowl surrounded by dried botanicals and smooth stones.Which Peptides Are Discussed in Perimenopause, and How Do They Fit With HRT?PT-141 is the only peptide FDA-approved for low desire. How it fits with HRT, plus CJC-1295, ipamorelin and GHK-Cu in perimenopause.

06Energy

Make sense of what affects your energy, then get to know the treatments that can help. See how they work, who they're for and what they cost.

Your HOD plan

Put your goals into a plan.

Clearer skin, fuller hair, a sex drive you're excited about. Tell us what you're after and see your HOD plan.

See My Plan